Breast Cancer Prevention

by Dr. S on November 15th, 2009

For those of you who have or have had breast cancer (BC), or know someone close that has, my heart goes out to you - I can relate. However, and this is a huge however, how many of you are doing everything possible to prevent it? Wearing something pink and walking to stir up awareness is commendable, but waiting for a cure is not enough.Taking responsibility by doing everything humanly possible to prevent getting breast cancer is more commendable and more beneficial. How many of you, without BC, but potentially at risk, have checked the following:

1. BRCA1 and BRCA2 genetic mutations via blood testing: BRCA1 and BRCA2 are human genes known as tumor suppressors, and mutations of these genes has been linked to hereditary breast and ovarian cancer.
2. Estradiol and progesterone imbalances in both blood and saliva: Either high levels of estradiol or low levels of progesterone results in "estrogen dominance." Too much estrogen (estradiol) exposure over time, without the counterbalancing effects of progesterone, predisposes one to potential estrogen positive cancers of the breast and uterus.
3. Estrogen metabolite levels and ratios in either blood or urine: How estrogen is being processed in the body can be assessed via serum or urine metabolite assessment - 16 alpha-hydroxyestrone and 2-hydroxyestrone are the two metabolites measured. The ratio of these metabolites can determine one's risk for breast cancer as well as other diseases including osteoporosis.
4. Body mass index (BMI), body fat percentage and waist circumference measurements: A BMI higher than 25, body fat percentage more than 25% (females) and/or a waist measurement (belly button) more than half your height in inches are all red flags and increase your risk for breast and other cancers, heart disease, and diabetes. Your waist measurement should be less than half your height in inches. Example: a 5'4" (64") female's waist measurement should be less than 32 inches, more than that would be considered abdominal (central-visceral) obesity. Excessive visceral fat cells produce various chemicals that cause systemic inflammation, and these same fat cells produce estrogen via testosterone conversion.
5. Periodic self-examination of breasts for lumps
6. Periodic checkups by your doctor

Prevention Tips

1. Lose body fat (weight): Strive for optimum BMI, body fat percentage and waist circumference
2. Exercise daily: Cross-train (aerobic and resistance training)
3. Eliminate processed and fast-foods including sweetened beverages from your diet - eliminate foods that contain high fructose corn syrup, sucrose and partially hydrogenated oils (soy, canola or vegetable)
4. Reduce or eliminate alcohol consumption
5. Stop smoking
6. Stop using synthetic hormone replacement (synthetic estradiol and progestin)
7. Counterbalance elevated estradiol levels with natural-bioidentical progesterone
8. Counterbalance elevated estradiol and 16 alpha-hydroxyestrone levels with flaxseed meal and flaxseed oil, fish oils (EPA/DHA), calcium-d-glucorate, cruciferous vegetables (Brussels spouts, broccoli, cauliflower, cabbage, etc) or their derivatives indole-3-carbinol (I3C) and diindolylmethaine (DIM)
9. Consume organic whole foods and foods rich in photochemicals and high ORAC (antioxdiant) value: spices, cocoa, colorful fruits and vegetables
10. Replace plastic food and beverage containers with glass or stainless steel. Avoid buying cans made with epoxy liners that leach bisphenol-A - buy BPA-free cans and bottles.
11. Take control of your health by changing your lifestyle, focus on becoming healthy and fit - Follow the principles taught in The Naked Truth: Overweight, Overhwelmed and Confused

Dr. Sardone


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